2021年1月6日 星期三

Light at the end of tunnel?

The most talk about issue locally here in Hong Kong remains the epidemic and the vaccine in the pipeline. With the absence of the dictatorship type of containment measures that is practiced in China, the western world as well as the democratic countries in Asia including Hong Kong are still struggling on the recent wave of the novel coronavirus. With the recent delivery of the vaccine, the whole world just sees the vaccine as the silver bullet to the dilemma as well as the economic resurgence. It seems as long as the vaccine is widely available to the general public then life will resume to normal so will the economy be.

Maintaining hope in life is important as to the drive to overcome difficulties, looking through rose-tinted glasses might bring more bad than good though. Let alone whether the so far major three vaccines available are proven to be effective is still not yet clinically certified, in fact none of them has finished the phrase III testing. The vaccine efficacy rate are all self claimed by the producers only. The most important point remains none of the producer is able to confirm the length of protection, even if the self-claimed efficacy rate is really valid. 

The whole world is forced to gamble on the effectiveness of these vaccines, sadly the price is that a vast numbers of people is to be the guinea pigs. According to the news, the vaccines do not have the supposed reception from the general public and this comes with good reason because despite the immediate serious side-effect rate after the vaccination so far is not high but since these vaccines have yet finished the normal and official testing process, the risks on the long term side-effect cannot be ruled out. 

The other concern on these vaccines is that the protection is unlike the other previously proven ones for other diseases that they can provide a comprehensive protection like immunity to infection and stops transmission even if infected, these three vaccines are not capable to stop transmission, at least no confirmation has ever made by the producers. Therefore even people take risk to be vaccinated yet the transmission chain will not be broken even if many people are vaccinated because the best self-claimed efficacy rate is 95% by the Pfiser followed by 94.1% by Moderna while Sinovac's has only 79% as self-claimed figure. Those infected even after vaccination can keep transmitting the disease unknowingly.

In a nutshell, resting the hope on the vaccine that it can end the pandemic thus the world can resume to normal and the world economy resurgence is just a wishful thinking. Let alone in reality people from the poor countries will not have access to vaccination so even if there is full vaccination in the rich countries the global transmission chain will never end indeed. The most optimistic forecast can only be the domestic resumption to normal within the rich countries on the basis that there is a nationwide full vaccination which is another wishful thinking.

On the other hand, while the whole world is putting its hope on the vaccine but it seems only little concern was put on the fact that vaccination is just a race against the viruses/germs because these microbes are constantly evolving and most of all, at a very fast rate which is way faster than the human's ability on vaccines development. In fact there were already more than 20 mutations found just in U.K. alone. Naturally not all mutations could bring more serious symptom or even more deadly but it is not whether or not but just a matter of time that a more deadly mutation is for sure in the pipeline as whether the more future mutations will become more friendly or deadly is just a random chance. Therefore chances are that before the western rich nations can achieve enough herd immunity through vaccination on their people, the Virus could has already mutated into a variation that the current vaccines are no longer protective leading the previous effort in vain. Let alone those poor nations are even not vaccinated due to financial constrain.

Higher the expectation, bigger disappointment will be when things turn out otherwise. As Trump's famous saying, we'll wait and see.